Less Label, More Light: What a 3D Microscopy Foundation Model Actually Buys
Microscopy has a labor problem. Not the photogenic kind where a scientist leans into a glowing instrument and discovers the secret architecture of life before lunch. The duller problem is that modern light sheet fluorescence microscopy can produce rich three-dimensional volumes faster than expert teams can label them. Segmentation requires voxel-level masks. Stain classification requires domain knowledge. Restoration needs paired degraded and high-quality images, which nature, unhelpfully, does not always provide in tidy folders. ...