AI Infrastructure

Opening — Why this matters now Large language models are no longer starved for text. They are starved for structure. As RAG systems mature, the bottleneck has shifted from whether we can retrieve information to how we decide where to look first, how far to go, and when to stop. Most retrieval stacks still force an early commitment: either search broadly and stay shallow, or traverse deeply and hope you picked the right starting point. ...

Opening — Why this matters now Large language models are getting cheaper to run, not because GPUs suddenly became charitable, but because we keep finding new ways to make models forget precision without forgetting intelligence. Post-training quantization (PTQ) is one of the most effective tricks in that playbook. And yet, despite years of algorithmic polish, PTQ still trips over something embarrassingly mundane: the calibration data. ...

Opening — Why this matters now 2025 quietly settled an uncomfortable truth in AI: agents are not products, they are supply chains. Anyone can demo a tool-using model. Very few can make it survive contact with real environments, long-horizon tasks, and users who refuse to behave like benchmarks. The paper “Let It Flow: Agentic Crafting on Rock and Roll” arrives at exactly this inflection point. Instead of promising yet another agent, it asks a more grown-up question: what kind of ecosystem is required to reliably produce agents at scale? ...

Opening — Why this matters now For years, AI for Science has celebrated isolated breakthroughs: a protein folded faster, a material screened earlier, a simulation accelerated. Impressive—yet strangely unsatisfying. Real science does not happen in single model calls. It unfolds across reading, computing, experimentation, validation, revision, and institutional memory. The uncomfortable truth is this: as AI accelerates scientific output, it is quietly breaking the human systems meant to verify it. Peer review strains. Reproducibility weakens. “It worked once” becomes the dominant success metric. ...

Google’s new in‑production measurement rewrites how we think about the environmental footprint of AI serving—and how to buy it responsibly. Executive takeaways A typical prompt is cheaper than you think—if measured correctly. The median Gemini Apps text prompt (May 2025) used ~0.24 Wh of energy, ~0.03 gCO2e, and ~0.26 mL of water. That’s about the energy of watching ~9 seconds of TV and roughly five drops of water. Boundaries matter more than math. When you count only accelerator draw, you get ~0.10 Wh. Add host CPU/DRAM, idle reserve capacity, and data‑center overhead (PUE), and it rises to ~0.24 Wh. Same workload, different boundaries. Efficiency compounds across the stack. In one year, Google reports ~33× lower energy/prompt and ~44× lower emissions/prompt, driven by model/inference software, fleet utilization, cleaner power, and hardware generations. Action for buyers: Ask vendors to disclose measurement boundary, batching policy, TTM PUE/WUE, and market‑based emissions factors. Without these, numbers aren’t comparable. Why the world argued about “energy per prompt” Most public figures were estimates based on assumed GPUs, token lengths, and workloads. Real fleets don’t behave like lab benches. The biggest source of disagreement wasn’t arithmetic; it was the measurement boundary: ...

Retrieval-Augmented Generation (RAG) is often hailed as a cure-all for domain adaptation and factual accuracy in large language models (LLMs). By injecting external context at inference time, RAG systems promise to boost performance on knowledge-intensive tasks. But a new paper, RAG in the Wild (Xu et al., 2025), reveals that this promise is brittle when we leave the sanitized lab environment and enter the real world of messy, multi-source knowledge. ...

Graph Neural Networks (GNNs) have come a long way since they solved Cora and PubMed node classification. But what happens when you want to model an entire traffic network, a biomedical knowledge graph, or a social graph with billions of nodes? That’s where PyG 2.0 steps in. The Industrialization of GNNs PyTorch Geometric (PyG) has been a dominant tool in the academic development of GNNs. With PyG 2.0, it graduates into the world of industrial-strength machine learning. This isn’t just a library update—it’s a fundamental re-architecture with three goals: ...

Introduction Generative AI continues to impress with its breadth of capabilities—from drafting reports to designing presentations. Yet despite these advances, it is crucial to understand the evolving cost structure, risk exposure, and strategic options businesses face before committing to full-scale AI adoption. This article offers a structured approach for business leaders and AI startups to evaluate where and when generative AI deployment makes sense. We explore cost-performance tradeoffs, forward-looking cost projections, tangible ROI examples, and differentiation strategies in a rapidly changing ecosystem. ...