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One Model, Two Label Spaces, and a Boundary Tradeoff

TL;DR for operators A healthcare AI team may want one segmentation system for uterine ultrasound and MRI, even when the datasets identify different anatomical structures. Topology-informed Prompt-conditioned Universal Segmentation (TPUS) addresses this problem by combining dataset-specific input processing with shared feature learning and class-conditioned prediction.1 Across 82 held-out cases from two datasets, TPUS leads seven competing complete methods on segmentation overlap and average boundary distance. Yet its improvements over the strongest baseline are modest. ...

October 30, 2026 · 7 min · Zelina