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When More Context Hurts: RareDx Treats Knowledge Use as a Governed System Component

TL;DR for operators Giving a decision-support model access to more knowledge is not the same as making it use knowledge well. In the controlled comparisons reported by RareDx, static retrieval can perform worse than direct inference, phenotype-aware structured retrieval can materially improve diagnostic coverage, and a validation-selected router can outperform using one inference strategy everywhere. ...

October 5, 2026 · 8 min · Zelina