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Blinded by Design: When AI Stops Thinking and Starts Remembering

A name can do a suspicious amount of work. Give an LLM a table of colorectal cancer gene candidates and ask it to rank the best drug targets. When the gene names are visible, KRAS lands at #1. The model justifies the choice with a confident reference to “proven therapeutic tractability via covalent RAS inhibitors.” Sensible enough, if the task is to combine the supplied table with the model’s accumulated biomedical knowledge. ...

April 8, 2026 · 19 min · Zelina